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article · Sultan Qaboos University medical journal

Efficacy of Hormonal and Non-Hormonal Vaginal Gel Preparations on the Female Sexual Satisfaction Index in Postmenopausal Women with Sexual Dysfunction Syndrome: A PRISMA-<i>compliant meta-analysis</i>

Abstract

We aimed to compare efficacy of vaginal gel preparations versus placebo in postmenopausal women with sexual dysfunction syndrome. We searched electronic databases from inception to January 2023. We included trials reporting Female Sexual Function Index (FSFI) which compared hormonal (estrogen, oxytocin) and/or non-hormonal (chamomile, fennel) interventions versus placebo. We used Cochrane Risk of Bias assessment tool I to evaluate studies quality. Eight trials (N=672 participants) were included. Total FSFI endpoint score was higher in the vaginal gel preparations group (MD: 6.67; 95% CI: [3.79, 9.55]; p Keywords: menopause, psychological sexual dysfunction, estrogen, Chamomile, Meta-analysis

Research topics

  • Sexual function and dysfunction studies
  • Menopause: Health Impacts and Treatments
  • Pelvic floor disorders treatments

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DOI: 10.18295/squmj.6.2024.040

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