review · Diabetology & Metabolic Syndrome

Efficacy and safety of glucagon-like peptide-1 receptor agonists on prediabetes: a systematic review and meta-analysis of randomized controlled trials

Hazem Mohamed Salamah
Salem Elshenawy
Khaled Alsayed Abualkhair
Mohamed Abugdida
Zhanna Zavgorodneva
Ahmed Marey
Anastasiia Tsyunchyk
Wael Atif Fadl Elhassan
Ronelle Bailey
Mostafa Mahmoud Naguib
Dmitrii Malnev
Lena Ibrahim
Jamrose Durrani
Andleeb Sherazi

202419 citationsOpen accessZagazig University

Abstract

GLP-1RAs combined with lifestyle modification proved to be a more effective therapy for managing prediabetic patients than lifestyle modification alone, with a tolerable safety profile. Future guidelines should consider GLP-1RAs as an adjunct to lifestyle modification in the management of prediabetic patients to provide better management and improve treatment adherence.

Research topics

Diabetes Treatment and Management
Pharmacology and Obesity Treatment
Metabolism, Diabetes, and Cancer

Sustainable Development Goals

3Good Health and Well-being

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DOI: 10.1186/s13098-024-01371-3

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