Effectiveness of Anatomic Reconstruction of the Middle Hepatic Vein in Right Lobe Graft Living Donor Liver Transplantation Using Natural Portal Vein Graft and Synthetic Graft

Abstract

Abstract Background LDLT using the right lobe is now a standard method for adults to alleviate the problem of graft size insufficiency. Without including MHV into RLG may cause sever congestion in the segment V and VIII which leads to graft dysfunction and septic complications. Objective This study was conducted to evaluate the efficacy of reconstructing the MHV in RLG LDLT with native portal vein graft versus synthetic graft. Methodology: This study involved 40 patients eligible for LDLT and was divided into, group A had synthetic graft reconstruction and group B had native PV graft reconstruction, while controlling for patient characteristics. Results In our study, 13 cases (32.5%) of postoperative venous graft thrombosis were recorded, with a higher incidence in the synthetic graft group (45.0%) compared to the native PV graft group (20.0%). However, the trend was not statistically significant. Timing-wise, thrombosis was observed earlier in the synthetic graft group. The existence of reconstructed veins V5 and V8 was associated with a higher incidence of thrombosis in the synthetic graft group. Sepsis was also found to be a potential risk factor, but with no statistical significance. Conclusion In adult LDLT with right lobe graft, the native PV graft should be the first choice for MHV reconstruction. The patency rate of the native PV graft was higher than synthetic graft, especially in cases with multiple veins requiring multiple venous anastomosis, which led to a decreased incidence of thrombosis.