Effect of Ramadan Fasting on Chronic Kidney Disease Patients

Abstract

This prospective cohort study evaluated the impact of Ramadan fasting on 162 patients with chronic kidney disease (CKD) and end-stage renal disease (ESRD) on regular hemodialysis. Participants were categorized based on fasting behavior and renal status. Biochemical and clinical parameters were assessed before, during, and after Ramadan. Results indicated that fasting was generally well-tolerated, though significant transient increases in blood urea, potassium, and phosphate were observed during fasting periods, particularly among ESRD patients fasting on dialysis days. Serum sodium and eGFR showed significant declines over time in both fasting and non-fasting CKD groups. No adverse effects on albumin or creatinine stability were noted in appropriately supervised patients. The study concludes that Ramadan fasting can be safe for stable CKD and ESRD patients with careful monitoring, dietary management, and individualized medical supervision to mitigate metabolic fluctuations.