Effect of Diet Mediated Immune Optimization on Blood Pressure

Abstract

A bstract Background: Good diet improves immune functionality and it is beneficial for blood pressure control. A personalized food avoidance dietary approach to stop hypertension (PFADASH) addresses primary and secondary immune intolerances of different individuals to different foods as well as exposures to toxic food substances responsible for inflammatory immune dysfunction that mediate hypertension. Objectives: We appraised the impact of diet mediated immune optimization on blood pressure. Materials and Methods: This was a longitudinal study and part of clinical trials to improve immune functionality via a personalized food avoidance dietary approach to stop hypertension (PFADASH) approved by the University of Nigeria Teaching Hospital Ethics Committee. A dietary compliance score of GOOD, FAIR, or POOR was based on the frequency of exposure to dietary ingredients suspected to drive adverse gene expression. Results: Study participants with poor dietary compliance had higher BP scores with higher variability compared to those with good dietary compliance, although the difference between the scores was not significant ( P > 0.05). Conclusion: A PFADASH although may serve as an immune optimizer and a therapeutic adjunct for blood pressure control does not significantly reduce the BP scores.