EFFECT OF ADENOTONSILLECTOMY ON PULMONARY HYPERTENSION SECONDARY TO ADENOTONSILLAR HYPERTROPHY

Abstract

Introduction Adenotonsillar hypertrophy (ATH) is a common condition in children, often leading to nasal obstruction, obstructive sleep apnea (OSA), and other systemic complications. One significant but vague consequence is pulmonary hypertension (PH), which arises from chronic upper airway obstruction, intermittent hypoxia, and reduced nitric oxide (NO) bioavailability. NO, produced primarily in the paranasal sinuses, plays a crucial role in pulmonary vasodilation. This study aimed to evaluate the prevalence of PH in children with ATH and assess the impact of adenotonsillectomy on PH. Objectives1-Estimate the prevalence of pulmonary hypertension in children with adenoidal or adenotonsillar hypertrophy.2- Assess the impact of adenotonsillectomy on pulmonary hypertension in affected patients..MethodsStudy Design:Part 1: Comparative cross-sectional study conducted to screen all participants for PH and to identify associated factors.Part 2: Interventional prospective study assessing the effect of adenotonsillectomy on PAP in echocardiography-confirmed cases. Participants: 150 children under 18 years scheduled for adenoidectomy or adenotonsillectomy, excluding children with preexisting cardiac or pulmonary conditions. Conducted at the Department of Otorhinolaryngology, Faculty of Medicine, Alexandria University.