Echocardiography versus Troponin I level as an indicator of sepsis induced myocardial dysfunction.

Abstract

Background: The leading causes of death and morbidity in American intensive care units are sepsis and septic shock. It has long been recognized that myocardial dysfunction can occur alongside acute organ dysfunction in cases of severe sepsis and septic shock. Aim and objectives: Analyzing the specificity and sensitivity of Troponin I and Echocardiography in detecting sepsis-induced myocardial dysfunction was the primary objective of the study. Subjects and methods:Thirty adults (ranging in age from 30to70) admitted to the Surgical Intensive Care Unit at El-Minia University Hospital with diagnoses of sepsis,severe sepsis,or septic shock between June 2023 and April 2024 were part of this prospective observational study.Prior to admission and again after 48 hours,patients were observed for vital signs,SOFA scores,and underwent troponin I tests. Result: According to the laboratory data collected from the participants under study,the average hemoglobin level was 10.93± 2.39 at baseline,10.57± 1.92 after 24 hours,and 10.53± 1.83 after 48 hours.Similarly,the average total leucocytic count was 28.21±9.15,27.20±8.32 after48 hours,and 26.50±9.89 after48 hours.After 24 hours and 48 hours,the average platelet count dropped to 263.43±116.88 and 231.53±109.39,respectively,from 284.67±139.25.The results of the EF analysis revealed an accuracy of 0.690 (0.495-0.845)with a standard error of 0.089, Conclusion: Our study found that blood troponin I(cTnI)levels might be a simple and useful way to track heart damage in septic patients who are very sick. Echocardiographic evidence points to a variety of cardiac dysfunctions in patients with an increased troponin I (cTnI) level.