article · AIDS
Early ART initiation in children with perinatal HIV (CHIV) greatly improves long-term outcomes. However, little is known of the long-term inflammatory profile. Our longitudinal study compared 26 inflammatory markers in early treated CHIV and HIV-unexposed children. CHIV displayed extensive immune marker elevations, clustered around monocyte activation. Despite early-antiretroviral therapy and sustained viral suppression, these children are at increased risk of non-communicable diseases.
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DOI: 10.1097/qad.0000000000004505
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