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article · African Research Journal of Medical Sciences

Doppler velocimetry of the prostate and its relationship with biochemical index in patients with benign prostate hyperplasia in Kano

2025Open accessGombe State University

In plain language

Benign prostatic hyperplasia is a non-malignant enlargement of the prostate that causes lower urinary tract symptoms in older men. A clinical study evaluated eighty male patients aged between fifty and eighty-five over an eight-month period to examine blood flow resistive index values. Among fifty-two evaluated patients, sixty-five per cent exhibited urinary blockage, which was characterised by markedly elevated resistive index readings in both the right and left capsular arteries. Prostate-specific antigen values were elevated in seventy-four per cent of the patients and were directly linked to enlargement in the capsular arteries. The findings show that resistive index measurements obtained through prostate Doppler ultrasound can effectively correlate with prostate size, antigen levels, and the degree of urinary obstruction, confirming its utility as an additional diagnostic modality.

Key takeaways

  • Markedly elevated resistive index values in the right and left capsular arteries indicate urinary obstruction in patients with benign prostatic hyperplasia.
  • Prostate-specific antigen levels were high in seventy-four per cent of the studied patients and were directly affected by capsular enlargement.
  • Resistive index measurements taken with Doppler ultrasound correlate closely with prostate size, antigen concentrations, and urinary obstruction.
  • Prostate Doppler ultrasound offers a viable complementary diagnostic modality for assessing benign prostatic hyperplasia.

Why it matters

Benign prostatic hyperplasia widely affects ageing men, leading to uncomfortable and disruptive urinary issues. Identifying reliable diagnostic markers is crucial for managing the condition. Showing that Doppler ultrasound measurements of prostate blood flow relate directly to physical obstruction and antigen levels provides clinicians with a valuable, non-invasive method to evaluate disease severity and improve patient assessments.

Commercialisation angle

This applied research indicates potential applications in ultrasound imaging and diagnostic decision-support tools for urologists and sonographers. Medical device manufacturers and clinical software developers could incorporate resistive index analysis into standard prostate ultrasound workflows to assist obstruction assessment. The findings represent early-stage clinical evidence that would require broader multi-centre validation before being established in commercial diagnostic protocols.

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Abstract

Background: Benign Prostatic Hyperplasia (BPH) is a non-malignant prostate gland enlargement that produces lower urinary tract symptoms in older men.This study investigates the Resistive Index (RI) of blood flow in prostate patients diagnosed with Benign Prostatic Hyperplasia (BPH).It compares the RI values of patients with obstructive BPH, non-obstructive BPH, high Prostate-Specific Antigen (PSA) levels, and aberrant prostate size.Materials and Methods: The study studied 80 male patients aged 50-85 with benign prostate hyperplasia and lower urinary tract symptoms during 8 months.Results: The blockage rate was 65% out of 52 patients, with 35% not having it.An obstructive pattern was shown by the markedly elevated resistance index of the right and left capsular arteries.Prostate Specific Antigen (PSA) values were high in 74% of patients and low in 26%.Additionally, PSA levels were directly impacted by the enlargement of the right and left capsular.Conclusion: The RI measurement using prostate Doppler ultrasound can be added to the modalities available for diagnosis of BPH.Moreover, its value can be correlated to the prostate size, prostate-specific antigens, and degree of obstruction.

Research topics

  • Prostate Cancer Diagnosis and Treatment
  • Urinary Bladder and Prostate Research
  • Urologic and reproductive health conditions

Read the original research

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DOI: 10.62587/afrjms.2.2.2025.82-87

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