Does Blood Pressure Control Have an Impact on Right Ventricular Systolic Function Assessed by 2-D Speckle Tracking Echocardiography?

Abstract

The main cardiovascular risk factor related to higher likelihood of heart failure is hypertension (HTN). There are plenty of researches on the pathological effects of HTN on the morphology and structure of the left ventricle (LV), but research investigating right ventricle (RV) mechanics in patients with hypertension have just recently emerged. So we aimed to assess whether blood pressure controlled or not had an impact on the systolic function of the RV.Methods: One hundred seventy two participants were assessed by 2D echocardiography for LV function m-mode, right ventricle RV including tissue doppler imaging(TDI) to evaluate RV myocardial performance index (MPI), RV s wave, tricuspid annular plane systolic excursion(TAPSE). Speckle tracking study was done for global longitudinal strain (GLS) of LV RV, and free wall strain.Results: Total of 172 participants were divided into, 86 were hypertensive in group I and 86 were normotensive in group II. TAPSE, MPI, RV s wave, PASP, LV-GLS, GLS of RV, and free wall strain were lower in group I. Subgroup analysis showed lower RVGLS in uncontrolled hypertensive patients.Conclusion: Uncontrolled hypertensive patients had lower RV-GLS in comparison to controlled hypertensive patients. The predictors of impaired RV GLS in uncontrolled BP patients were BMI, RV MPI, and LVGLS