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article · AIDS Research and Therapy

Distribution of CCR5-Delta32, CCR2-64I, and SDF1-3’A host genetic factors in HIV-infected and uninfected individuals in Luanda, Angola

Abstract

We found no CCR5-Delta32 allele, while CCR2-64I and SDF1-3'A were found and presented a relationship with HIV infection, age, ABO/RH blood group, and HIV-1 subtypes. The observed associations of CCR2-64I and SDF1-3'A with HIV underscore the urgent need for further multidisciplinary research, with potential implications for targeted prevention and public health strategies. Therefore, studies investigating biological and non-biological factors related to susceptibility to HIV infection and AIDS progression or death should be conducted in Angola.

Research topics

  • HIV Research and Treatment
  • HIV/AIDS drug development and treatment
  • Virology and Viral Diseases

Sustainable Development Goals

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DOI: 10.1186/s12981-025-00751-7

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