Diffuse leptomeningeal enhancement with optic nerve involvement in a patient with intracranial hypertension as the inaugural symptom of neurosarcoidosis

Abstract

A 43-year-old female patient having a known history of pulmonary sarcoidosis presented with a rapidly developing intracranial hypertension, followed by a state of drowsiness. Cerebral MRI revealed intense leptomeningeal contrast enhancement and thickening of the pituitary gland. The present report detailed the primary imaging abnormalities observed in the patient and highlighted the importance of considering a differential diagnosis within the context of the clinical picture The clinical approach supporting the inflammatory origin of the observed imaging abnormalities in this case is discussed. Furthermore, this case highlighted the rapid effect of cortiotherapy in improving the neurological dysfunctions associated with neurosarciodosis which can be life-threatening.