Different Methods for Preparation of Hydroxyapatite Nanostructures

Abstract

Hydroxyapatite could be utilized as a bioceramic owing to its osteoconductivity and bioactivity characteristics. It is obvious that the shape of HAp nanoparticles clearly influences their properties such as bioactivity and surface area. Nano-sized HAp particles with different morphologies were synthesized using a variety of preparation processes such as solvothermal, microwave-solvothermal, precipitation and hydrothermal-precipitation process. The effect of preparation methods on particle morphology was studied. The X-ray diffraction (XRD), Fourier-transform infrared spectroscopy (FTIR), transmission electron microscopy (TEM), scanning electron microscopy (SEM), and Zeta potential (ZP), were used to validate the composition and structure of the as-formulated HAp nanostructures. A single phase of HAp was obtained using various methods of preparation. According to the TEM analysis of the powders, both the solvothermal and the hydrothermal treatment samples were very diffuse and consisted of fairly homogeneous HAp nanorods.