article · Frontiers in Pharmacology

Development and pharmacokinetic evaluation of granisetron hydrochloride buccal tablets for optimized chemotherapy-induced nausea and vomiting (CINV) relief

Chandrashekar Thalluri
Bayapa Reddy Narapureddy
Sarad Pawar Naik Bukke
Vinod Kumar Yata
Jharna Medhi
Ananda Kumar Chettupalli
Malliukarjun Vasam
Bharath Kumar Mamilla Mugaiahgari
Ravi Chander Thatipelli

2026Open accessKampala International University

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Abstract

The optimized buccal system provides controlled release and enhanced pharmacokinetic performance, suggesting a promising alternative approach for effective CINV management.

Research topics

Nausea and vomiting management
Chemotherapy-induced organ toxicity mitigation
Complementary and Alternative Medicine Studies

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DOI: 10.3389/fphar.2026.1731072

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