Determination of the Prevalence of Blood Transfusion among Children with Different ABO and Rhesus Blood Group Systems: A Systematic Review and Meta-Analysis

Abstract

Background: Blood transfusion is a common medical intervention in pediatric patients.However, the prevalence of blood transfusion amongst children with different ABO/Rhesus blood group types have been not well established and documented due to lack of data and paucity knowledge.Objective: The current study is aimed at conducting a systematic review of published literature to determine the prevalence of blood transfusion amongst children with different ABO/Rhesus blood group systems.Methods: A comprehensive literature search was conducted using different search engines, including PubMed, Scopus, and Web of Science, Google Scholar, Embase, Cochrane Library, CINAHL, PsycINFO, ScienceDirect, ProQuest etc. Out of 400 articles retrieved, 300 articles were selected for inclusion in this review. Results:The results of this review showed that the prevalence of blood transfusion amongst children with different ABO/Rhesus blood types varied widely.Children with blood group types such as O + , B + , A + and AB + were more likely to receive blood transfusion, while those with blood group A -, B -, AB -, and O -types were less likely to receive blood transfusion.Conclusion: This systematic review highlights the importance of considering ABO/Rhesus blood types in pediatric patients requiring blood transfusions.Further studies are needed to fully understand the benefits of blood transfusions in children population.