Determinant of post-transurethral resection of the prostate acute urinary retention at Tibebe ghion specialized hospital, Northwest Ethiopia: unmatched case-control study 2023

Abstract

Abstract Background Transurethral resection of the prostate (TURP) is recognized as the gold standard for alleviating bladder outlet obstruction associated with benign prostatic hyperplasia (BPH). Despite its efficacy, TURP can be accompanied by various complications, including acute urinary retention, which undermines the intended outcome. However, there is limited evidence available regarding the factors contributing to post-TURP acute urinary retention. Methods A hospital-based unmatched case-control study assessed patients undergoing transurethral resection of the prostate (TURP). Excluding those with diagnoses like prostatic cancer and Parkinsonism, data were analyzed using SPSS version 23. Bivariate and multivariable logistic regression identified factors for post-TURP acute urinary retention, with p-values under 0.05 deemed significant. Results Among 143 audited cases, 40 fell into the AUR group, while 103 were non-AUR. Variables like age, illness duration, preoperative AUR, prostate volume > 80 ml, and showed increased AUR likelihood but lacked statistical significance. In incompletely resected adenomatous tissue, surgery duration > 60 min, intraoperative urethral injury, prolonged catheterization (> 2 days), and postoperative UTI had significantly higher AUR odds. Multivariate analysis revealed incomplete resection as the sole sustained significant variable (AOR = 8.34, 95%CI (2.21–31.65)). Conclusions Incomplete resection emerged as a significant predictor of post-TURP AUR. Vigilance, thorough preoperative assessments, and consideration of specific factors are crucial for optimal outcomes. Further studies are warranted to validate these findings, given the study’s limitations.