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article · Journal of Biomolecular Structure and Dynamics

Design, synthesis and biological evaluation of pyrazolo[3,4- <i>b</i> ]pyridine derivatives as dual CDK2/PIM1 inhibitors with potent anti-cancer activity and selectivity

202512 citationsOpen accessPharos University in Alexandria

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Abstract

as a promising dual CDK2/PIM1 inhibitor with potent anti-cancer activity and selectivity, paving the way for its further optimization and development as a lead molecule in cancer therapy.

Research topics

  • Cancer Mechanisms and Therapy
  • Synthesis and Biological Evaluation
  • Bioactive Compounds and Antitumor Agents

Sustainable Development Goals

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DOI: 10.1080/07391102.2025.2475233

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