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article · Frontiers in Cellular and Infection Microbiology

Derangements of immunological proteins in HIV-associated diffuse large B-cell lymphoma: the frequency and prognostic impact

20243 citationsOpen accessUniversity of the Witwatersrand

Abstract

Derangements of immunological proteins are common in HIV-DLBCL, and have a differential association with survival compared to that reported elsewhere. Elevation of TGFβ, IL-10 and ferritin were associated with survival independently from the IPI. In view of the poor survival rates in this cohort, investigation of the directed targeting of these cytokines would be of interest in our setting.

Research topics

  • Lymphoma Diagnosis and Treatment
  • Viral-associated cancers and disorders
  • Chronic Lymphocytic Leukemia Research

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DOI: 10.3389/fcimb.2024.1340096

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