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article · Cancer Reports

Cytotoxicity Potency of Cannabinoids Is by Serum Supplementation: Implications for In Vitro Cancer Studies

2026Open accessUniversity of Pretoria

Abstract

The study demonstrates that serum concentration critically modulates the cytotoxic potency of cannabinoids. Reduced FCS enhances cannabinoid efficacy by limiting protein binding, emphasizing the need to optimize serum conditions for accurate in vitro cytotoxicity assessments.

Research topics

  • Cannabis and Cannabinoid Research
  • Forensic Toxicology and Drug Analysis
  • Alcohol Consumption and Health Effects

Sustainable Development Goals

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DOI: 10.1002/cnr2.70520

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