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article · RSC Advances

Cutting-edge biomaterials for advanced biomedical uses: self-gelation of <scp>l</scp> -arginine-loaded chitosan/PVA/vanillin hydrogel for accelerating topical wound healing and skin regeneration

202412 citationsOpen accessBritish University in Egypt

Abstract

biological assays are conducted to confirm the effectiveness of the prepared hydrogel in promoting wound healing and bone regeneration through cytotoxicity assay and wound scratch assay. The composite hydrogels achieved 95% wound healing after 24 hours, attributed to the release of NO from the loaded l-Arg and its essential role in the wound healing process. Consequently, CH-PVA-Van hydrogels emerge as a promising system for loading l-arginine and exhibiting potential for biomedical applications with antibacterial efficacy.

Research topics

  • Biochemical and biochemical processes
  • Microencapsulation and Drying Processes
  • Bee Products Chemical Analysis

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DOI: 10.1039/d4ra04430d

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