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article · Asian Pacific Journal of Cancer Prevention

Crosstalk between ZEB1 expression and CD163+ Tumor-Associated Macrophages in Muscle-Invasive Urothelial Carcinoma

2026Open accessAssiut University

Abstract

Elevated ZEB1 expression is strongly associated with poor prognosis in BC and closely correlated with an increased density of CD163+TAMs, further contributing to adverse outcomes. These findings highlight the potential of ZEB1 as a prognostic biomarker and underscore the therapeutic relevance of targeting TAMs in the management of BC.

Research topics

  • Bladder and Urothelial Cancer Treatments
  • Immune cells in cancer
  • Tissue Engineering and Regenerative Medicine

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DOI: 10.31557/apjcp.2026.27.2.499

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