article · Indian Journal of Anaesthesia

Comparison of dexmedetomidine, haloperidol, and propofol sedation on intra-abdominal pressure, inflammatory response, and clinical outcomes in patients with abdominal sepsis: A randomised controlled study

Sherif Kamal Arafa
Ahmed Abdelhamid
Asmaa Abdelbadie
Shaimaa Abdelbadie
Mostafa M. Shaheen
Ahmed A.A. Shama

2026Open accessBeni Suef University

Abstract

Dexmedetomidine exhibited superior anti-inflammatory effects and better control of IAP than haloperidol and propofol in abdominal sepsis patients. However, these physiological improvements did not translate into significant differences in clinical outcomes.

Research topics

Abdominal Surgery and Complications
Sepsis Diagnosis and Treatment
Respiratory Support and Mechanisms

Sustainable Development Goals

3Good Health and Well-being

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DOI: 10.4103/ija.ija_647_25

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