review · Journal of Computer Assisted Tomography
Arterial spin labeling provides several clinical applications across the diagnosis, staging, and monitoring of brain tumours. This imaging technique helps distinguish neoplastic conditions from non-neoplastic lesions, including brain infarction and infection. In oncology, it supports the grading of gliomas and aids in differentiating them from other malignancies such as lymphomas and metastatic disease. Clinicians can also employ the method to locate optimal biopsy sites and predict how tumours may respond to therapy. Beyond initial assessment, arterial spin labeling assists in evaluating extra-axial and paediatric brain tumours. It also plays an important role following treatment by differentiating tumour recurrence from changes caused by radiation therapy, enabling ongoing surveillance and follow-up care for patients who have completed therapeutic procedures.
Accurate brain tumour diagnosis and ongoing monitoring are essential for effective clinical management. Arterial spin labeling provides insights that clarify complex scans, helping medical teams differentiate true tumours from infections or treatment side effects. This guidance supports more precise biopsy planning, better assessment of treatment responses, and clearer detection of whether a cancer has returned after radiation therapy.
The abstract outlines applied clinical imaging uses of arterial spin labeling for radiologists, neuro-oncologists, and surgical teams. These applications centre on diagnostic software, imaging protocols, and decision-support tools for tumour grading, biopsy guidance, and post-radiation follow-up. Because the abstract details existing clinical roles rather than experimental prototypes, the underlying imaging approach appears applied and tested in medical settings.
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The aim of this review was to review the basic background, technique, and clinical applications of arterial spin labeling in brain tumors. Arterial spin labeling is used for differentiation of brain tumors from nonneoplastic lesions such as infarction and infection. It has a role in the grading of gliomas and in the differentiation of gliomas from lymphomas and metastasis. It is used for detection of the best biopsy site and prediction of treatment response. Arterial spin labeling is used for the assessment of extra-axial tumors and pediatric tumors. Last, it has a role in the differentiation of tumor recurrence from postradiation changes and in monitoring patients after therapy.
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DOI: 10.1097/rct.0000000000000873
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