article · Malaria Journal

Chloroquine has shown high therapeutic efficacy against uncomplicated Plasmodium vivax malaria in southern Ethiopia: seven decades after its introduction

Anteneh Kassahun Mare
Henok Hailgiorgis
Mebrahtom Haile
Gudissa Assefa
Sarah Auburn
Worku Bekele
Jonathan B. Parr
Solomón Mequanente Abay
Rick Price
Geremew Tasew
Jonathan J. Juliano
Heven Sime
Kale Gubae
Bekuretsion Gidey
Hussein Mohammed
Ashenafi Assefa

20243 citationsOpen accessDebre Markos University

Abstract

Despite previous reports of declining chloroquine efficacy against P. vivax, CQ retains high therapeutic efficacy in southern Ethiopia, supporting the current national treatment guidelines. Ongoing clinical monitoring of CQ efficacy supported by advanced molecular methods is warranted to inform national surveillance and ensure optimal treatment guidelines.

Research topics

Malaria Research and Control
Mosquito-borne diseases and control
Drug-Induced Hepatotoxicity and Protection

Sustainable Development Goals

Good Health and Well-being

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DOI: 10.1186/s12936-024-05009-7

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