article · Pest Management Science
This study has demonstrated that chitosan-based dsRNA nanomaterials can significantly improve the stability of dsRNA in the midgut fluid, enhance RNAi efficiency, and increase insect mortality. Moreover, chitosan-based dsRNA delivery enhances silencing efficiency by increasing the uptake of dsRNA in the epidermal cells. Our results suggest that the use of chitosan nanomaterial for dsRNA delivery is a feasible strategy for advancing the application of RNAi technology in pest management. © 2025 Society of Chemical Industry.
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DOI: 10.1002/ps.8880
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