article · Alzheimer s & Dementia

Cerebrospinal fluid fatty acids are better predictors of mild cognitive impairment than Aβ <sub>42</sub> /tau ratio

Jacob Apibilla Ayembilla
Yannick N. Wadop
Xueqiu Jian
Bernard Fongang
Biniyam Ayele
Jayandra J. Himali
Alice Nono Djotsa
Muralidharan Sargurupremraj
Alfred K. Njamnshi
Sudha Seshadri
Alfred N. Fonteh

2025Open accessAccra Technical University

Abstract

Our study suggests that changes in fatty acid metabolism precede abnormalities in amyloid and tau in MCI. Thus, strategies that regulate fatty acid metabolism may stem off early cognitive decline in an older population.

Research topics

Dementia and Cognitive Impairment Research
Fatty Acid Research and Health
Cerebrospinal fluid and hydrocephalus

Sustainable Development Goals

Good Health and Well-being

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DOI: 10.1002/alz70856_102952

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