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preprint · F1000Research

Case Report: Mepolizumab in the treatment of idiopathic chronic eosinophilic pneumonia

20232 citationsOpen accessUniversity of Tunis El Manar

Abstract

Idiopathic chronic eosinophilic pneumonia (ICEP) is a rare interstitial lung disease of unknown cause. It usually responds well to systemic corticosteroid therapy, but relapses are frequent. We describe two cases of 21- and 27-year-old patients, presenting with dyspnea. The diagnosis of steroid-relapsing and steroid-dependent ICEP was made respectively. Mepolizumab was prescribed to both patients. This treatment resulted in successful long-term disease management with much fewer side effects than a traditional corticosteroid therapy.

Research topics

  • Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
  • Eosinophilic Disorders and Syndromes
  • Eosinophilic Esophagitis

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DOI: 10.12688/f1000research.130939.2

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