review · Frontiers in Veterinary Science
Brucellosis remains one of the most hazardous zoonotic infections globally, causing substantial economic losses across developed and developing nations. Despite extensive eradication programmes, the pathogen continues to spread widely. Recent initiatives have demonstrated effective strategies for the prevention and control of bovine brucellosis, offering models for wider containment efforts. To support these goals, research has synthesised current knowledge on the global distribution of Brucella species, the predisposing factors that drive emerging strains, and host immune mechanisms. Furthermore, the synthesis examines existing vaccine types alongside contemporary genomics and proteomics tools integrated into brucellosis investigation. By establishing an updated overview of surveillance data, molecular technologies, and control perspectives, this baseline provides a consolidated foundation for researchers developing future scientific strategies to manage and eliminate these highly contagious pathogens from animal and human populations.
Brucellosis threatens livestock productivity and human health across the globe, driving substantial economic disruption in agriculture. Synthesising global patterns of spread, vaccine technologies, and advanced molecular methods helps guide future intervention programmes. Clearer insight into pathogen biology and control mechanisms is crucial for protecting livestock herds, securing agricultural livelihoods, and reducing the incidence of dangerous animal-to-human disease transmission.
While the abstract outlines vaccines, genomics, and proteomics approaches for managing bovine brucellosis, it focuses on guiding future academic research rather than immediate product development. Potential practical applications lie in informing veterinary vaccine design and molecular diagnostic strategies. These pathways remain at an early review and research-planning stage, with no specific commercial products, readiness levels, or industry partnerships described in the text.
AI-generated from the published abstract. Always read the original work before citing.
Brucellosis is considered one of the most hazardous zoonotic diseases all over the world. It causes formidable economic losses in developed and developing countries. Despite the significant attempts to get rid of Brucella pathogens in many parts of the world, the disease continues to spread widely. Recently, many attempts proved to be effective for the prevention and control of highly contagious bovine brucellosis, which could be followed by others to achieve a prosperous future without rampant Brucella pathogens. In this study, the updated view for worldwide Brucella distribution, possible predisposing factors for emerging Brucella pathogens, immune response and different types of Brucella vaccines, genomics and proteomics approaches incorporated recently in the field of brucellosis, and future perspectives for prevention and control of bovine brucellosis have been discussed comprehensively. So, the current study will be used as a guide for researchers in planning their future work, which will pave the way for a new world without these highly contagious pathogens that have been infecting and threatening the health of humans and terrestrial animals.
This page summarises published work. The authoritative version sits with the publisher.
DOI: 10.3389/fvets.2023.1255239
Is something wrong with this record? Report it or request removal.
Discussion
Have you built on this work, tried to replicate it, or seen it applied in practice? Share what you know. Verified researchers and MARATTO™ domain experts can open a discussion, and any member can reply. Contributions are reviewed before they appear.
No discussion yet. Open the first thread.
New to MARATTO™? Create a free account.
