article · Frontiers in Digital Health

Breaking barriers: harnessing artificial intelligence for a stigma-free, efficient HIV prevention assessment among adults in South Africa

Rebecca Berhanu
Candice Chetty-Makkan
Sasha Frade
Rouella Mendonca
Natalie Maricich
Dino Rech
Lawrence Long
Sarah Morris
Yohann Richard
Ross Greener
Sophie Pascoe

2026Open accessUniversity of the Witwatersrand

Abstract

An LLM-powered conversational agent like "Your Choice" shows promise for private, stigma-free HIV prevention support, including PrEP uptake, supporting the decision-making around PrEP initiation. It can also help providers deliver more targeted care. Future research should address technological trust and clinical integration.

Research topics

HIV/AIDS Research and Interventions
Mobile Health and mHealth Applications
Digital Mental Health Interventions

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DOI: 10.3389/fdgth.2025.1731002

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