Brachial Artery Thrombosis following Cisplatin-Based Chemotherapy of Cholangiocarcinoma – A rare occurrence

Abstract

Abstract Thromboembolism is the cause of significant mortality and morbidity in cancer patients. While the link between cancer and venous thrombosis is well known, the recognition of arterial thrombosis as a serious complication of cancer and chemotherapeutic agents is a recent development. One of the chemotherapy agents frequently linked to acute vascular events is cisplatin. We discuss the rare case of cisplatin-related brachial arterial thrombosis in a 50-year-old man from Ethiopia who was undergoing treatment for cholangiocarcinoma with cisplatin and gemcitabine chemotherapy. Although rare, cisplatin-related arterial thrombosis demands careful monitoring, a high index of suspicion, and prompt management to prevent serious morbidity and mortality.