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article · Journal of Pharmacy and Pharmacology

Black mulberry fruit extract alleviates streptozotocin-induced diabetic nephropathy in rats: targeting TNF-α inflammatory pathway

Abstract

The ameliorative effect of BMFE on diabetic nephropathy is not only through its potent antioxidant and hypoglycaemic effects but also through its downregulation of TNF-α, VCAM-1 and fibronectin mRNA expression in renal tissues of diabetic-treated rats. Therefore, BMFE as dietary supplement could be a promising agent in improving diabetic nephropathy.

Research topics

  • Ginger and Zingiberaceae research
  • Advanced Glycation End Products research
  • Natural Antidiabetic Agents Studies

Sustainable Development Goals

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DOI: 10.1111/jphp.13338

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