article · Bioorganic Chemistry

Biphenyl urea derivatives as novel GPX4 inhibitors: ferroptosis-mediated antiproliferative activity against CNS cancer cells

Wagdy M. Eldehna
Heba A. Elsebaie
Anwar A El-Hamaky
Salma M. Hefny
Heba Aref
Haytham O. Tawfik
Moataz A. Shaldam

2026Menoufia University

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Research topics

Ferroptosis and cancer prognosis
Cholesterol and Lipid Metabolism
TGF-β signaling in diseases

Sustainable Development Goals

3Good Health and Well-being

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DOI: 10.1016/j.bioorg.2026.109714

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