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article · Antibiotics

Bedaquiline Resistance in Drug-Resistant Tuberculosis in South Africa: A Systematic Review and Meta-Analysis of Emerging Trends

2026Open accessUniversity of Limpopo

Abstract

Bedaquiline remains effective for DR-TB treatment in South Africa; however, emerging resistance and its molecular drivers pose a growing threat to regimen sustainability, including BPaL. Strengthened surveillance and standardized resistance testing are urgently needed.

Research topics

  • Tuberculosis Research and Epidemiology
  • Malaria Research and Control
  • Pharmaceutical Quality and Counterfeiting

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DOI: 10.3390/antibiotics15040385

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