article · Clinical Case Reports
Autoimmune hepatitis (AIH) following COVID-19 vaccination is a rare adverse event. We present the case of a 55-year-old male with a history of ulcerative colitis (UC) who developed AIH 3 weeks after receiving his second dose of the Pfizer-BioNTech mRNA vaccine. He presented with jaundice and significantly elevated liver enzymes. A liver biopsy confirmed the diagnosis of AIH. The patient was successfully treated with corticosteroids and azathioprine, leading to complete clinical and biochemical remission. This case highlights the potential for vaccine-induced autoimmune phenomena, particularly in individuals with preexisting autoimmune conditions, and underscores the importance of prompt diagnosis and treatment.
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DOI: 10.1002/ccr3.72686
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