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article · BMC Genomics

Association of relative expression of HSD11B-1 and HSD11B-2 with pregnancy status in sheep

2025Open accessAlexandria University

Abstract

To the best of our knowledge, this study is the first to report a significant upregulation of both genes as early as day 12 post-mating, providing a new benchmark for early pregnancy detection, which previously focused on day 14. This insight into gene expression patterns provides valuable information for reproductive biology and may inform future breeding and management practices aimed at optimizing reproductive success in sheep.

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DOI: 10.1186/s12864-025-12186-5

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