article · Vector-Borne and Zoonotic Diseases

Application of Long-Read Sequencing for Genotyping, Epigenetic Profiling and Surveillance of <i>Yersinia pestis</i> Isolates from Natural Foci and Disease Outbreaks in Central Asia

Aigul Abdirassilova
Zauresh Zhumadilova
Gulnara Zh. Tokmurziyeva
Altynai Kassenova
Duman T. Yessimseit
Altyn K. Rysbekova
Arnat S. Dikhanbayev
Altyn Rysbekova
Beсk Z Abdeliyev
Duman T Yessimseit
Sanzhar D Agzam
Vladimir L Motin
Vladimir L. Motin
Oleg N. Reva
Oleg N. Reva

2026University of Pretoria

Abstract

These findings demonstrate the effectiveness of long-read sequencing technologies in revealing both genetic and epigenetic features of bacterial pathogens, contributing to our understanding of the evolutionary mechanisms underlying the emergence and spread of this especially dangerous infection.

Research topics

Yersinia bacterium, plague, ectoparasites research
Genomics and Phylogenetic Studies
Vibrio bacteria research studies

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DOI: 10.1177/15303667261427352

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