article · Microorganisms

Antimicrobial and Anti-Efflux Machinery of FDA-Approved Proton Pump Inhibitors and Vitamins Against Klebsiella pneumoniae and Pseudomonas aeruginosa

Lekaa L. Lutfi
Moataz A. Shaldam
Mona I. Shaaban
Soha Lotfy Elshaer

2025Open accessKafr el-Sheikh University

Abstract

This study highlights the anti-efflux activity of ESO, OME, PAN, VD, and VK against the tested Gram-negative strains. Hence, these PPIs and vitamins could be valuable adjuvant treatments to enhance the effectiveness of curing infections caused by MDR strains.

Research topics

Antibiotic Resistance in Bacteria
Phenothiazines and Benzothiazines Synthesis and Activities
Computational Drug Discovery Methods

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DOI: 10.3390/microorganisms13061227

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