Antibacterial Effects of Laser in Treating Contaminated Wounds

Abstract

Bacterial infections persist as a major worldwide health issue. Regarded as the most distressing factor affecting the wound healing process, resulting in prolonged healing time, increased patient trauma, elevated treatment expenses, and substantial mortality and morbidity. The prevalence of antibiotic resistance among bacteria has led to the emergence of bacterial wound infection as an alarming and complex health issue. The effectiveness of traditional antibiotic treatments is progressively limited, prompting the exploration of alternative therapeutic approaches. Antibacterial Photodynamic Therapy (aPDT) using laser technology has shown great potential in treating persistent bacterial infections. This review aims to provide an extensive overview of different wound treatment strategies and infection management modalities within and surrounding the wound bed as well as the use of aPDT against different bacterial pathogens, with a particular focus on its potential to tackle the worldwide problem of bacterial infections.