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article · Scientific Reports

Antibacterial activity of selected plants used in traditional medicine from Gedeo zone, Ethiopia against multidrug-resistant wound bacterial isolates

Abstract

µg/mL. The time-kill kinetics showed a dose-dependent bactericidal activity against P. aeruginosa, achieving a ≥ 3 log₁₀ colony forming units/mL (CFU/mL) reduction within 2 h at concentrations of 4× and 8× MIC. This research examines the antibacterial effects of extracts from various parts of three selected plants, substantiating their traditional use in treating wound infections and providing a baseline for future investigation. It also highlights the probable ethnobotanical uses of O. lamiifolium; in particular, which may be a promising candidate in the search for new antimicrobial drugs.

Research topics

  • Ethnobotanical and Medicinal Plants Studies
  • Andrographolide Research and Applications
  • Essential Oils and Antimicrobial Activity

Sustainable Development Goals

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DOI: 10.1038/s41598-026-55836-8

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