article · Endocrine Metabolic & Immune Disorders - Drug Targets
In a dose-dependent manner, acyclovir and <i>Pavetta indica</i> methanolic extract treatments abrogated the streptozotocin-induced behavioral and neurological abnormalities in rats. The potential therapeutic effects of PIME and acyclovir administration in intracerebroventricular-streptozotocin-treated rats may be attributed to its potential antiviral, antioxidant, and anti-inflammatory effects. The current study suggests that <i>Pavetta indica</i> methanolic extract and acyclovir are promising therapeutic targets against Alzheimer's disease.
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DOI: 10.2174/0118715303273145240110100341
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