article · RSC Advances

Ancistrolikokines E–H and related 5,8′-coupled naphthylisoquinoline alkaloids from the Congolese liana<i>Ancistrocladus likoko</i>with antiausterity activities against PANC-1 human pancreatic cancer cells

Shaimaa Fayez
Doris Feineis
Virima Mudogo
Suresh Awale
Gerhard Bringmann

201728 citationsOpen accessUniversité de Kinshasa (UNIKIN)

Abstract

A striking feature of the metabolite profile of<italic>Ancistrocladus likoko</italic>(Ancistrocladaceae) is the exclusive production of 5,8′-linked naphthylisoquinoline alkaloids with strong activities against pancreatic cancer cells.

Research topics

Axial and Atropisomeric Chirality Synthesis
Sphingolipid Metabolism and Signaling
Cancer therapeutics and mechanisms

Sustainable Development Goals

3Good Health and Well-being

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DOI: 10.1039/c7ra11200a

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