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article · Frontiers in Veterinary Science

Ameliorative effects of vitamin C and garlic (Allium sativum) on nifedipine-induced reproductive dysfunction in a male albino rat model

2026Open accessUniversity of Nigeria

Abstract

Nifedipine caused significant impairments in sperm quality and histological integrity. Vitamin C and garlic combination produced a statistically significant improvement in normal sperm morphology, with other parameters showing non-significant numerical increases. Further research with larger sample sizes and biochemical analyses is needed to clarify the extent of antioxidant influence on nifedipine-induced reproductive alterations.

Research topics

  • Garlic and Onion Studies
  • Chemotherapy-induced organ toxicity mitigation
  • Sperm and Testicular Function

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DOI: 10.3389/fvets.2025.1725725

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