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review · Molecular Therapy — Nucleic Acids

Advanced delivery systems for gene editing: A comprehensive review from the GenE-HumDi COST Action Working Group

202541 citationsOpen accessAbdelmalek Essaâdi University

In plain language

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Abstract

approaches, often representing a barrier to achieving the desired editing efficiency and safety. In this review, authored by members of the GenE-HumDi European Cooperation in Science and Technology (COST) Action, we described the plethora of delivery systems available for genome-editing components, including viral and non-viral systems, highlighting their advantages, limitations, and potential application in a clinical setting.

Research topics

  • CRISPR and Genetic Engineering
  • Virus-based gene therapy research
  • Viral Infections and Immunology Research

Sustainable Development Goals

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DOI: 10.1016/j.omtn.2025.102457

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