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article · European Journal of Case Reports in Internal Medicine

A spectacular effect of tocilizumab in Takayasu arteritis

20241 citationOpen accessUniversity of Tunis El Manar

Abstract

Background: Anti-interleukin-6 receptors (anti-IL-6R) have been a promising new therapeutic alternative in the treatment of Takayasu arteritis. Case description: We report the case of a 34-year-old patient with Takayasu arteritis diagnosed in 2017. While she was on corticosteroid and methotrexate, the patient presented twice with clinical and radiological signs of activity, requiring an increase of corticosteroid dose and an increase in the methotrexate dose to 20 mg/week. Anti-IL-6R infusions were indicated. At the end of the fifth infusion, the patient was totally asymptomatic: she no longer experienced episodes of syncope or amnesia. Conclusion: Our case perfectly illustrates the effectiveness of anti-IL-6R in the treatment of Takayasu arteritis, especially in its refractory form. LEARNING POINTS: Takayasu arteritis may have a significant functional impact that affects quality of life.Tocilizumab is a very interesting therapeutic alternative in the refractory form of Takayasu arteritis.

Research topics

  • Vasculitis and related conditions
  • Renal Diseases and Glomerulopathies
  • Adrenal Hormones and Disorders

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DOI: 10.12890/2024_004868

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