A Novel Biosensor for Non-Invasive Blood Glucose Measurement Based on Double Square Complimentary Split Ring Resonator

Abstract

Planar microwave sensors are considered a promising solution to measure blood glucose levels non-invasively. A novel metamaterial microwave biosensor is presented, consisting of a double square complementary split-ring resonator (CSRR) over the frequency range (0-7 GHz). This unique structure is novel in this application. The main concept of the proposed sensor is the concentrated, confined electric field over the sensing region, which results in sensitivity enhancement. The double CSSR sensor is theoretically studied and numerically modelled using Computer Simulation Technology (CST) software. The sensor’s sensitivity is illustrated through simulation in the range of 40-500 mg/dL. In-vitro, experiments are held using de-ionized water glucose solutions within the clinical diabetic range. Results show a high sensitivity performance up to 0.0056 dB/(mg/dL). Hence, our sensor ensures the capability of monitoring the glucose changes either for hypo (40 mg/dL) or hyperglycemia (500 mg/dL) cases non-invasively.