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review · NEJM Evidence

A Meta-Analysis of Levofloxacin for Contacts of Multidrug-Resistant Tuberculosis

202430 citationsOpen accessUniversity of the Witwatersrand

Abstract

In this meta-analysis of two randomized trials, levofloxacin was associated with a 60% relative reduction in TB incidence among adult and child household MDR-TB contacts, but with an increased risk of musculoskeletal adverse events. (Funded by the Australian National Health and Medical Research Council, UNITAID, and others.).

Research topics

  • Tuberculosis Research and Epidemiology
  • Pneumocystis jirovecii pneumonia detection and treatment
  • Infectious Diseases and Tuberculosis

Sustainable Development Goals

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DOI: 10.1056/evidoa2400190

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