article · European J of Industrial Engineering
The use of home hemodialysis (HHD) has the potential to lower healthcare costs while improving quality-adjusted survival and quality of patient's life. Nevertheless, the number of patients on this modality of dialysis remains low due to several barriers among which the problem of storage capacity. In fact, patients have a limited storage capacity in their homes, so they cannot store the required consumables (i.e., commodities) for long-term treatment sessions. Therefore, to promote HD use by dialysis patients, healthcare systems should offer flexible service that satisfies the patient's need in term of delivery frequency. Getting inspired by the periodic vehicle routing problem (PVRP), we develop here a mathematical formulation of the considered problem, and we propose a new approach based on the general variable neighbourhood search metaheuristic (GVNS) to solve it, due to its NP-hardness. To illustrate the effectiveness of the proposed approach, several tests have been performed. [Received: 9 August 2022; Accepted: 23 March 2023]
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DOI: 10.1504/ejie.2024.138215
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