article · Journal of drug targeting

A Dual-Action nanoemulsified mucoadhesive polymeric buccal film of curcumin–lidocaine: non-Invasive targeting oral mucositis treatment via MMP-9 and NF-κβ pathways

Sammar Fathy Elhabal
Shahinaze A. Fouad
Mahmoud H. Teaima
Mohamed G. Farahat
Nahla A. Elzohairy
Mohamed El-Nabarawi

20263 citationsModern University for Information and Technology

Abstract

, the CUR-LID film significantly enhanced ulcer healing (∼95-100% by day 5), with complete mucosal regeneration and normalisation of inflammatory biomarkers to baseline levels. This work supports the CUR-LID buccal film as a prospective non-invasive platform for managing oral mucositis with better therapeutic outcomes, effective drug delivery, and prolonged mucosal contact.

Research topics

Oral health in cancer treatment
Advanced Drug Delivery Systems
Bone health and treatments

Sustainable Development Goals

3Good Health and Well-being

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DOI: 10.1080/1061186x.2026.2613056

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