article · QJM
Abstract Background Human papillomavirus (HPV) is the most common viral infection of the reproductive tract in women and men. Although most HPV infections resolve spontaneously, persistent infections can lead to precancerous lesions and cancer of the cervix, vagina, vulva, anus and penis. HPV related cancers accounted for an estimated 4.5% of all cancers worldwide in 2012. Objective To describe the patients’ demographic features, clinical presentations, sexual aspects, and possible risk factors of codyloma accuminata among female patients treated at Dermatology, venereology and Andrology outpatient clinics of Ain Shams University hospitals and Al-Houd Al-Mrsoud hospital, Cairo, Egypt. Patients and Methods This prospective cross sectional clinical study was conducted on 500 female patients aged above 18 years old with condyloma accuminata. Results Most of the studied patients (71.2%)gave a history of no condom use, (13.7%) of patients gave history of occasional condom use while the rest 7.5% weren’t sexually active. Most of the patients (61.3%) gave a history of cryotherapy, (8.6%) patients gave a history of chemical cautery, (4.5%) patients gave a history of electro surgery and (2.1%) patients gave a history of immunotherapy. Among the studied patients those had chemical cautery as a treatment modality had the highest recurrence rate. Conclusion The main risk factors for condyloma accuminata are young age, unprotected sexual intercourse, multiple sex partners and lower socioeconomic and educational levels. Smoking or alcohol together with immunosuppressive medications and chronic diseases as well as other STDs are possible risk factors. History of medical intervention as laser hair removal of genital area, colonoscopy and vaginal ultrasound could play a role in condyloma accuminata transmission in non-sexual active women. Condyloma accuminata occurred in more than one genital sites in relation to laser hair removal of genital areas compared to mostly one site in sexual transmission.
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DOI: 10.1093/qjmed/hcae175.201
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