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article · Indian Journal of Nuclear Medicine

18F-FDG PET/CT in Lung Hepatoid Adenocarcinoma

2025Open accessMohammed V University

Abstract

Hepatoid adenocarcinoma of the lung (HAL) is an exceptionally rare and highly aggressive form of extrahepatic adenocarcinoma. Characterized by alpha-fetoprotein production and exhibiting morphological features akin to hepatocellular carcinoma, it poses significant diagnostic and therapeutic challenges. We present the case of a 39-year-old male with a history of smoking, who sought medical attention for right-sided chest pain, cough, and difficulty breathing. Imaging studies, including a chest X-ray and ¹⁸F-FDG PET/CT scan, revealed a pulmonary mass with intense FDG uptake. Further pathological analysis confirmed the diagnosis of HAL, highlighting the importance of early recognition and accurate diagnosis of this rare malignancy.

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DOI: 10.4103/ijnm.ijnm_71_25

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